Histone acetylation inhibitors promote axon growth in adult dorsal root ganglia neurons
نویسندگان
چکیده
منابع مشابه
Histone acetylation inhibitors promote axon growth in adult dorsal root ganglia neurons.
Intrinsic mechanisms that guide damaged axons to regenerate following spinal cord injury remain poorly understood. Manipulation of posttranslational modifications of key proteins in mature neurons could reinvigorate growth machinery after injury. One such modification is acetylation, a reversible process controlled by two enzyme families, the histone deacetylases (HDACs) and the histone acetyl ...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Research
سال: 2015
ISSN: 0360-4012
DOI: 10.1002/jnr.23573